What is Cefadroxil?
This is the 1st generation cephalosporin antibiotic. It acts bactericidal (kills bacteria), due to the ability to inhibit the production of cell wall components.
Indications for use
Cefadroxil is prescribed:
- with respiratory tract infections;
- with infections of the ENT organs;
- with infections of the kidneys, urinary tract;
- with infections of the genital organs;
- with skin infections;
- with soft tissue infections;
- with infections of the abdominal cavity;
- with infections of joints, bones;
- with wound infections.
Cefadroxil cannot be used;
with an allergy to cephalosporins (with an allergy to penicillins, it is important to consider the possibility of a cross-reaction);
children under 6 years old.
Instructions for use
Cefadroxil is administered orally.
Dosage depends on the causative agent of the infection, the severity of the clinical condition.
Standard doses: adults, children from 12 years old — 1000 mg. If necessary, it is allowed to increase the dose to 3000-4000 mg / day. Children weighing up to 40 kg are shown 25–50–100 mg / kg / day.
With pharyngitis / tonsillitis, persons over 12 years of age are recommended 1000 mg 1 time / day. Children weighing up to 40 kg are shown 30 mg / kg / day.
In case of impaired renal function, the dose is selected based on the creatinine clearance indicator.
Pregnancy and lactation
This medicine is able to penetrate the placental barrier, therefore it is not used in pregnant women.
The active substance of this drug in low concentrations is excreted in breast milk, so breast-feeding is stopped during treatment.
Digestive disorders: diarrhea (loose stools), nausea, stomatitis (inflammation of the oral mucosa), glossitis (inflammation of the tongue), pancreatitis, obstruction (obstruction) of the biliary tract, pseudomembranous colitis.
Changes in the skin, subcutaneous tissue: rashes, urticaria, itching, edema, exanthema, erythema multiforme, allergic dermatitis, Lyell’s syndrome.
Common disorders: chills, dizziness, fever, headache, anaphylactic / anaphylactoid reactions.
Urinary disorders: oliguria, glucosuria, hematuria, kidney stone formation, renal failure.
Symptoms: vomiting, abdominal pain, diarrhea, hematuria, hyperreflexia, electrolyte imbalance, convulsions, hallucinations, extrapyramidal disorders, shock, drop in blood pressure, tachycardia / bradycardia, dyspnea, exanthema, acidosis, coma, renal failure.
In case of an overdose, the necessary symptomatic treatment, hemodialysis, is performed.